Trifarotol™

Trifarotol™ is a new era of retinoid science — precision-targeted to renew skin at its source, delivering smoother, clearer, more youthful-looking skin without the irritation traditionally associated with retinol.

Think of Trifarotol™ as retinol, evolved.

Instead of overwhelming the skin, this fourth-generation retinoid works in harmony with it — activating only the receptors that matter most for visible renewal. The result? Skin that looks smoother, brighter, and more refined over time, with none of the drama.

It’s powerful enough to visibly soften fine lines and improve texture, yet gentle enough for nightly use — making it the ideal hero ingredient in a modern night cream.

Why it’s different
Unlike traditional retinoids that activate multiple skin receptors (often causing redness or sensitivity), Trifarotol™ works smarter. It selectively targets the RAR-γ receptor — the receptor most abundant in the skin — allowing it to support renewal, collagen production, and clarity while being noticeably gentler on skin.

How it works
Once applied, Trifarotol™ is bio-transformed by the skin’s own enzymes into its active form, delivering results exactly where skin needs them most. This precision approach helps improve the look of fine lines, texture, tone, and overall radiance — without over-stimulating the skin barrier.

Visible results, proven gentle
In a 12-week clinical study, participants experienced significant improvements in skin smoothness, clarity, tone, and overall appearance — with 100% agreeing the ingredient felt gentle on their skin. Even delicate eye-area wrinkles visibly improved over time.

Why it’s perfect for nightly use
Trifarotol™ is gentle enough for daily application and highly stable, meaning it maintains its effectiveness without special packaging or additives. That makes it ideal for modern night creams designed to deliver consistent, long-term skin renewal.