Adapinoid® is the only third generation retinoid for cosmetic use. This novel active is a precursor of adapalene which is proven to increase collagen, reduce photoaging, balance skin tone, sooth inflammation, reduce pores, and clear acne-prone skin. Unlike first generation retinoids vitamin A types like retinol and retinoic acid), Adapinoid has far fewer toxicity, stability, and skin-irritation concerns.

Oleyl Adapalenate

Physical Description
White powder

Formulation Benefits

  • Oil-Soluble: Easy to formulate without ethanol or solvents
  • Completely Stable: No need for expensive airless packaging, nitrogen blanket filling, or restricted
  • storage conditions
  • Widely Recognized: Accepted by dermatologists and consumers, without the regulatory hassle of an API drug



  • Suggested use level: 0.5% minimum
  • Add to oil phase and heat to 80⚬C. Mix until homogenous and proceed with phase combination
  • Works well in squalane-based oil phases. Can pre-dissolve in squalane prior to incorporating into oil phase
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