Prodrugs

In the science of pharmacology, a prodrug is a precursor compound that is inactive on its own, but can be converted to an active agent by the body’s own metabolic processes.

Our  skin is populated by a vast microbiome that produce enzymes. These enzymes, combined with topically applied prodrugs, together form a powerful tool for enhancing skin appearance, health and wellness.

The skin enzymes are the activator. They convert prodrug compounds into their active form, sometimes after the compound has already absorbed into deeper skin layers. The converted agent then exerts its bioactivity at the targeted site where it is needed.

Actera’s innovative prodrugs have proven to be the foremost technology for professional-grade consumer skincare. This approach addresses many of the limitations of traditional actives —such as instability, irritation, or inefficient absorption—by enabling more controlled activation, improved bioavailability, and consistent results.