Adapinoid®

U.S. Patent No. 12,133,907
Ultra Gentle Pro-Adapalene

INCI

Oleyl Adapalenate

Overview

Adapinoid® is the only third generation retinoid for cosmetic use. This novel active is a precursor of adapalene which is proven to increase collagen, reduce photoaging, balance skin tone, soothe inflammation, reduce pores, and clear acne-prone skin. Unlike first generation retinoids (vitamin A types like retinol and retinoic acid), Adapinoid has far fewer toxicity, stability, and skin-irritation concerns.

Adapinoid vs. Retinol

  • 2x greater wrinkle reduction
  • 10x greater redness reduction
  • 70x greater TEWL reduction
Off-white powder

• Suggested use level: 0.16 – 0.5% minimum
• Add to oil phase and heat to 80⚬C. Mix until homogeneous and proceed with phase combination

 

Smart Delivery System
Bio-transforms with the skin’s own enzymes to slowly release active adapalene into the skin layers

Targets Inflammaging
Adapalene is proven to inhibit the inflammatory pathways related to lipoxygenase (5-LOX and 15-LOX) activity in the skin compared to typical retinoids. Protective effect helps soothe skin, reduce redness, even skin tone, and reduce inflammation-related causes of aging

Clinical Efficacy Without Irritation
Considerably more gentle than traditional retinoids which are known to cause redness, itching, flaking, and stinging

Multi-Action Skin Perfecting
Tackles both aging and acne

Want to learn more about Adapinoid® ?
Formulations featuring Adapinoid®
Wrinkle Reduction
Global Redness Reduction

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